Journal article

EXCITATORY SYNAPTIC POTENTIALS DUE TO ACTIVATION OF NEURONS WITH SHORT PROJECTIONS IN THE MYENTERIC PLEXUS

JC BORNSTEIN, RA NORTH, M COSTA, JB FURNESS

NEUROSCIENCE | PERGAMON-ELSEVIER SCIENCE LTD | Published : 1984

Abstract

Intracellular microelectrodes have been used to examine the effects, on excitatory inputs to myenteric nerve cells, of lesions of intrinsic pathways in the myenteric plexus of the guinea-pig small intestine. The lesions consisted of circumferential cuts (myotomies) which severed the external musculature to the depth of the submucosa and thus interrupted pathways in the myenteric plexus. Sufficient time was allowed between creating the lesions and recording from the neurons for the endings of severed neurites to degenerate and this was confirmed histochemically by examining the distribution of varicose fibres with 5-hydroxytryptamine immunoreactivity in myenteric ganglia from which recordings..

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