Journal article

PROJECTIONS OF INTESTINAL NEURONS SHOWING IMMUNOREACTIVITY FOR VASOACTIVE INTESTINAL POLYPEPTIDE ARE CONSISTENT WITH THESE NEURONS BEING THE ENTERIC INHIBITORY NEURONS

JB FURNESS, M COSTA

NEUROSCIENCE LETTERS | ELSEVIER SCI IRELAND LTD | Published : 1979

Abstract

Experiments were performed to determine if the distribution of vasoactive intestinal peptide(VIP)-like immunoreactivity in nerve cell bodies and axons of the myenteric plexus and circular muscle of the small intestine is consistent with VIP being the transmitter of enteric inhibitory neurons. Immunoreactivity for VIP was found in nerve cell bodies of the myenteric plexus and in axons within the myenteric plexus and circular muscle. When the axons in the myenteric plexus were interrupted, there was accumulation of material showing reactivity for VIP on the oral side, indicating that the neurons project in an anal direction. The VIP-like immunoreactivity in axons which supply the circular musc..

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University of Melbourne Researchers