That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda
Stefan HI Kappe, Ashley M Vaughan, Justin A Boddey, Alan F Cowman
SCIENCE | AMER ASSOC ADVANCEMENT SCIENCE | Published : 2010
The global research community must take up the challenge to work toward the eradication of malaria. In the past, malaria research has focused on drugs and vaccines that target the blood stage of infection, and mainly on the most deadly species, Plasmodium falciparum, all of which is justified by the need to prevent and treat the disease. This work remains critically important today. However, an increased research focus is now being placed on potential interventions that aim to kill the parasite stages transmitted to and by the mosquito vector because they may represent more vulnerable targets to stop the spread of malaria. Here, we highlight some of the research into malaria parasite biology..View full abstract
Awarded by NIH
Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
We apologize to many in the field whose work we could not cite because of space constraints. S. H. I. K. is supported by a grant from the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiaitve and NIH grant R01 AI053709. A. F. C. is supported by the National Health and Medical Research Council (NHMRC) of Australia, NIH grant RO1 A144008, and an Australia fellowship and is an International Scholar of the Howard Hughes Medical Institute. J.A.B. is supported by a Peter Doherty Postdoctoral Fellowship from NHMRC.