Journal article

The autonomic nerve supply of male sex organs - an important target of circulating androgens

JR Keast

BEHAVIOURAL BRAIN RESEARCH | ELSEVIER SCIENCE BV | Published : 1999

Abstract

The autonomic nervous system plays a critical role in the regulation of smooth muscle contraction, exocrine secretion and blood flow in the male reproductive organs. Many of the autonomic neurons that supply these targets lie in the pelvic ganglia, which contain both sympathetic and parasympathetic ganglion cells. In rats, removal of circulating androgens by castration before or after puberty has profound effects on the structure, chemistry and function of particular classes of pelvic autonomic neurons. While most of these effects occur in reproductive pathways, some bladder- or bowel-projecting neurons also exhibit androgen-sensitivity. Our studies on these ganglion cells and their spinal p..

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University of Melbourne Researchers