Journal article

SELECTIVE ASSOCIATION OF NERVE-FIBERS IMMUNOREACTIVE FOR SUBSTANCE-P OR BOMBESIN WITH PUTATIVE CHOLINERGIC NEURONS OF THE MALE-RAT MAJOR PELVIC GANGLION

JR KEAST, HC CHIAM

CELL AND TISSUE RESEARCH | SPRINGER VERLAG | Published : 1994

Abstract

The male rat major pelvic ganglion contains both sympathetic and parasympathetic neurons that supply the lower urinary and digestive tracts, and the reproductive organs. The aim of this study was to describe the distribution and identify potential targets of sensory and intestinofugal axons in this ganglion. Two putative markers of these projections were chosen, substance P for primary sensory axons and bombesin for myenteric intestinofugal projections. Varicose substance P-immunoreactive axons were associated only with non-noradrenergic (putative cholinergic) somata, and most commonly with those that contained vasoactive intestinal peptide. Immunoreactivity for substance P was also present ..

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