Journal article
Risk factors for malaria and adverse birth outcomes in a prospective cohort of pregnant women resident in a high malaria transmission area of Papua New Guinea
DI Stanisic, KA Moore, F Baiwog, A Ura, C Clapham, CL King, PM Siba, JG Beeson, I Mueller, FJ Fowkes, SJ Rogerson
Transactions of the Royal Society of Tropical Medicine and Hygiene | OXFORD UNIV PRESS | Published : 2015
Abstract
Background: Low birth weight (LBW), anaemia and malaria are common in Papua New Guinean women. Methods: To identify risk factors for LBW, anaemia and preterm delivery (PTD), pregnant women recruited into a cohort study in Madang, Papua New Guinea, were followed to delivery. Results: Of 470 women enrolled, delivery datawere available for 328 (69.7%). By microscopy, 34.4% (113/328) of women had malaria parasitaemia at enrolment and 12.5% (41/328) at delivery; at each time point, PCR detected sub-microscopic parasitaemia in substantially more. Most infections were with Plasmodium falciparum; the remainder being predominantly P. vivax. Anaemia and smoking were associated with lower birth weight,..
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Awarded by Bill & Melinda Gates Foundation's Global Health Program
Funding Acknowledgements
This work was supported by AusAID (grant to PNG IMR), the National Health and Medical Research Council of Australia (project grants to JGB and SJR, Senior Fellowships to JGB and IM); Australian Research Council (Future Fellowship to FJF); Wellcome Trust (Senior Fellowship to SJR); and Veterans Affairs Research Service (to CLK). DIS was supported by a grant to the PNG Institute of Medical Research from the Bill & Melinda Gates Foundation's Global Health Program [# 34678]. The Burnet Institute and the Walter and Eliza Hall Institute are supported by the NHMRC Infrastructure for Research Institutes Support Scheme and Victorian State Government Operational Infrastructure Support.