Journal article

Projections of chemically identified myenteric neurons of the small and large intestine of the mouse

Q Sang, S Williamson, HM Young

JOURNAL OF ANATOMY | WILEY-BLACKWELL | Published : 1997

Abstract

The projections of different subpopulations of myenteric neurons in the mouse small and large intestine were examined by combining immunohistological techniques with myotomy and myectomy operations. The myotomies were used to examine the polarity of neurons projecting within the myenteric plexus and showed that neurons containing immunoreactivity for nitric oxide synthase (NOS), vasoactive intestinal peptide (VIP), calbindin and 5-HT projected anally, while neurons with substance P (SP)-immunoreactivity projected orally, in both the small and large intestine. Neurons containing neuropeptide Y (NPY)- and calretinin-immunoreactivity projected locally. In the large intestine, GABA-immunoreactiv..

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University of Melbourne Researchers