Journal article

Crystallography and New Medicines: Examples from Influenza and Cell Death

Peter M Colman

AUSTRALIAN JOURNAL OF CHEMISTRY | CSIRO PUBLISHING | Published : 2014

Abstract

Biomolecular crystallography underpins contemporary drug discovery. The author's experiences in early (influenza) and recent (cancer) examples mark progress in the sophistication of approaches that have enabled a shift from simpler problems, as in enzyme inhibition, to complex problems, as in blocking protein - protein interactions.

University of Melbourne Researchers

Grants

Funding Acknowledgements

I acknowledge current support from the National Health and Medical Research Centre (NHMRC), the Australian Cancer Research Foundation, the Leukaemia and Lymphoma Society (US), the Victorian State Government Operational Infrastructure Support, and the Australian Government NHMRC IRIISS.