Journal article

ELECTROPHYSIOLOGICAL RESPONSES IN THE RAT TAIL ARTERY DURING REINNERVATION FOLLOWING LESIONS OF THE SYMPATHETIC SUPPLY

P JOBLING, EM MCLACHLAN, W JANIG, CR ANDERSON

JOURNAL OF PHYSIOLOGY-LONDON | CAMBRIDGE UNIV PRESS | Published : 1992

Abstract

1. Responses to perivascular stimuli have been recorded with intracellular microelectrodes from the smooth muscle of isolated segments of the main caudal artery of rats at various times between 7 and 128 days after all four collector nerve trunks had been lesioned near the base of the tail at 21 days of age. 2. In proximal segments (< 40 mm distal to the lesions), excitatory junction potentials (EJPs) and neurogenic alpha-depolarizations (NADs) evoked by stimuli presented via a proximally located suction electrode were similar to those in the same segments of unoperated control animals of the same age. Supramaximal EJPs in these segments decreased in amplitude with age. 3. Stimuli just supra..

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University of Melbourne Researchers