Cryptosporidium cuniculus - New records in human and kangaroo in Australia

Abstract

Background: To date, Cryptosporidium cuniculus has been found exclusively in rabbits and humans. The present study provides the first published molecular evidence for C. cuniculus in an Australian human patient as well as a kangaroo. Findings: Using PCR-based sequencing of regions in the actin, 60 kDa glycoprotein (gp60) and small subunit of ribosomal RNA (SSU) genes, we identified a new and unique C. cuniculus genotype (akin to VbA25) from a human, and C. cuniculus genotype VbA26 from an Eastern grey kangaroo (Macropus giganteus) in Australia. Conclusions: The characterisation of these genotypes raises questions as to their potential to infect humans and/or other animals in Australia, given..