Journal article
Impact of early valve surgery on outcome of staphylococcus aureus prosthetic valve infective endocarditis: Analysis in the international collaboration of endocarditis-prospective cohort study
C Chirouze, F Alla, VG Fowler, DJ Sexton, GR Corey, VH Chu, A Wang, ML Erpelding, E Durante-Mangoni, N Fernández-Hidalgo, E Giannitsioti, MM Hannan, T Lejko-Zupanc, JM Miró, P Muñoz, DR Murdoch, P Tattevin, C Tribouilloy, B Hoen, L Clara Show all
Clinical Infectious Diseases | Published : 2015
DOI: 10.1093/cid/ciu871
Abstract
Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis-Prospective Cohort Study. Methods. Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients ..
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Awarded by National Institute of Allergy and Infectious Diseases
Funding Acknowledgements
This work was supported in part at Hospital Clinic of Barcelona (Spain) by grants from the Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III (Madrid, Spain); the Spanish Network for Research in Infectious Diseases (REIPI RD06/0008); Fondo de Investigaciones Sanitarias (Madrid, Spain) (grant FIS 1101131); and Fundacion Maximo Soriano Jimenez (Barcelona, Spain).