Journal article

Successful control of an outbreak of invasive aspergillosis in a regional haematology unit during hospital construction works

CC Chang, AC Cheng, B Devitt, AJ Hughes, P Campbell, K Styles, J Low, E Athan

JOURNAL OF HOSPITAL INFECTION | W B SAUNDERS CO LTD | Published : 2008

Abstract

We report the successful control of an outbreak of six cases of nosocomial invasive aspergillosis (IA) in our haematology unit coinciding with major hospital construction works. Infection control changes included unit relocation, impermeable barriers at construction site, face-masking and voriconazole prophylaxis of 18 further high-risk patients, none of which developed breakthrough IA. A multi-faceted pre-emptive approach involving clinicians, hospital management, engineering and building departments is essential in preventing nosocomial IA outbreaks.