Staphylococcus aureus endocarditis: A consequence of medical progress

VG Fowler; JM Miro; B Hoen; CH Cabell; E Abrutyn; E Rubinstein; GR Corey; D Spelman; SF Bradley; B Barsic; PA Pappas; KJ Anstrom; D Wray; CQ Fortes; I Anguera; E Athan; P Jones; JTM Van Der Meer; TSJ Elliott; DP Levine; AS Bayer

Journal article

Staphylococcus aureus endocarditis: A consequence of medical progress

VG Fowler, JM Miro, B Hoen, CH Cabell, E Abrutyn, E Rubinstein, GR Corey, D Spelman, SF Bradley, B Barsic, PA Pappas, KJ Anstrom, D Wray, CQ Fortes, I Anguera, E Athan, P Jones, JTM Van Der Meer, TSJ Elliott, DP Levine Show all

JAMA | AMER MEDICAL ASSOC | Published : 2005

DOI: 10.1001/jama.293.24.3012

Abstract

Context: The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives: To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants: Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure: In-hospital mortality. Results: S..

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