Left anterior cingulate activity predicts intra-individual reaction time variability in healthy adults
Beth P Johnson, Ari Pinar, Alex Fornito, L Sanjay Nandam, Robert Hester, Mark A Bellgrove
Neuropsychologia | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2015
Within-subject, or intra-individual, variability in reaction time (RT) is increasingly recognised as an important indicator of the efficiency of attentional control, yet there have been few investigations of the neural correlates of trial-to-trial RT variability in healthy adults. We sought to determine the neural correlates of intra-individual RT variability during a go/no-go response inhibition task in 27 healthy, male participants. We found that reduced trial-to-trial RT variability (i.e. greater response stability) was significantly associated with greater activation in the left pregenual anterior cingulate. These results support the role of the left anterior cingulate in the dynamic con..View full abstract
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Awarded by Australian Research Council
Awarded by Australian National Health and Medical Research Council
This work was supported by Australian Research Council Grant DP0770337 (Mark A. Bellgrove), the Australian National Health and Medical Research Council (Mark A. Bellgrove & Robert Hester, Grant 519730).