Journal article

Spectral- and time-domain optical coherence tomography measurements of macular thickness in normal eyes and in eyes with diabetic macular edema

MA Ibrahim, YJ Sepah, RCA Symons, R Channa, E Hatef, A Khwaja, M Bittencourt, J Heo, DV Do, QD Nguyen

EYE | NATURE PUBLISHING GROUP | Published : 2012

Abstract

PURPOSE: To report macular thickness values in normal eyes and eyes with diabetic macular edema (DME) using time-domain (TD) and spectral-domain (SD) optical coherence tomography (OCT), and to derive a conversion equation. METHODS: The index study was a prospective investigation conducted on 80 eyes from 40 normal subjects and 130 eyes from 118 patients with DME seen in our clinic. Retinal thickness values from the central 1 mm of the macula and surrounding four ETDRS subfields were acquired using TD-OCT (Stratus OCT) and SD-OCT (SPECTRALIS HRA+OCT). Measurements of the central (C) subfield from both devices were used to derive a conversion equation. The equation was used to predict SD-OCT v..

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University of Melbourne Researchers

Grants

Awarded by National Eye Institute, National Institutes of Health


Awarded by NATIONAL EYE INSTITUTE


Funding Acknowledgements

QDN is the recipient of the Physician Scientist Award from the Research to Prevent Blindness and the RO1 Award from the National Eye Institute, National Institutes of Health (EY17577). QDN, DVD, and the Johns Hopkins University have received research support from Heidelberg Engineering, Inc. QDN has served on the Scientific Advisory Board for Heidelberg, Inc. The remaining authors declare no conflict of interest.