Journal article
Dynamic and quantitative analysis of choroidal neovascularization by fluorescein angiography
Syed Mahmood Shah, Sinan Tatlipinar, Edward Quinlan, Jennifer U Sung, Homayoun Tabandeh, Quan Dong Nguyen, Ahmed S Fahmy, Ingrid Zimmer-Galler, RC Andrew Symons, Jesse M Cedarbaum, Peter A Campochiaro
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2006
DOI: 10.1167/iovs.06-0012
Abstract
PURPOSE: In this study, the authors sought to develop and characterize techniques for measuring changes in choroidal neovascularization (CNV) lesion size and fluorescence over time for quantitative analysis of fluorescein angiograms. METHODS: Initial assessment of the quantitative technique was made by retrospectively analyzing digital fluorescein angiograms taken before and 3 months after photodynamic therapy (PDT) for CNV (6 patients, group 1). The method was then applied prospectively to digital fluorescein angiograms (baseline and day 71) obtained on 12 patients taking part in a clinical trial investigating the effect of vascular endothelial growth factor (VEGF) Trap in CNV (group 2). Tw..
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