A multi-platform metabolomics approach demonstrates changes in energy metabolism and the transsulfuration pathway in Chironomus tepperi following exposure to zinc
Sara M Long, Dedreia L Tull, Katherine J Jeppe, David P De Souza, Saravanan Dayalan, Vincent J Pettigrove, Malcolm J McConville, Ary A Hoffmann
Aquatic Toxicology | ELSEVIER SCIENCE BV | Published : 2015
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The authors thank Rebecca Reid and Lee Engelstad for assistance with chironomid culture and the zinc exposures. We also thank Komal Kanojia, Sean O'Callaghan, James Pyke, Amsha Nahid and John Sheedy for assistance with optimization, extraction, quantification and analysis of metabolites. This project was funded by foundation funding granted to the Centre of Aquatic Pollution Identification and Management by The Victorian Science Agenda Investment Fund managed by the Department of Business and Innovation with partner funding contributed from Melbourne Water, Department of Primary Industries (Victoria), and Environment Protection Authority (Victoria) and by fellowships from the Australian Research Council (AHH & KJJ) and the Australian National Health and Medical Research Council (MJM).