The Effect of Ketamine on Configural Facial Processing
Erica Neill, Nicole Joshua, Celia Morgan, Susan L Rossell
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015
Ketamine can induce a transient psychosis via its influence on ionotropic N-methyl-d-aspartate receptors. Unlike dopamine agonists, which specifically mimic the positive symptoms seen in psychotic illnesses such as schizophrenia, ketamine may provide a better model because it is able to induce not only positive symptoms but also schizophrenia-like cognitive and negative symptoms. To test the veracity of the ketamine model further, research is attempting to replicate a range of cognitive deficits associated with schizophrenia in healthy controls under the influence of ketamine. Facial processing is one area that is impaired in schizophrenia. More specifically, research suggests that schizophr..View full abstract
Awarded by National Health and Medical Research Council Postdoctoral scholarship
Author Susan L. Rossell was funded by a National Alliance for Research on Schizophrenia and Depression Young Investigator Award to complete this research. Author Erica Neill has a National Health and Medical Research Council Postdoctoral scholarship (520451).