Journal article

The Effect of Ketamine on Configural Facial Processing

Erica Neill, Nicole Joshua, Celia Morgan, Susan L Rossell

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015

Abstract

Ketamine can induce a transient psychosis via its influence on ionotropic N-methyl-d-aspartate receptors. Unlike dopamine agonists, which specifically mimic the positive symptoms seen in psychotic illnesses such as schizophrenia, ketamine may provide a better model because it is able to induce not only positive symptoms but also schizophrenia-like cognitive and negative symptoms. To test the veracity of the ketamine model further, research is attempting to replicate a range of cognitive deficits associated with schizophrenia in healthy controls under the influence of ketamine. Facial processing is one area that is impaired in schizophrenia. More specifically, research suggests that schizophr..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council Postdoctoral scholarship


Funding Acknowledgements

Author Susan L. Rossell was funded by a National Alliance for Research on Schizophrenia and Depression Young Investigator Award to complete this research. Author Erica Neill has a National Health and Medical Research Council Postdoctoral scholarship (520451).