FRAX (Aus) and falls risk: Association in men and women
Kara L Holloway, Mark A Kotowicz, Stephen E Lane, Sharon L Brennan, Julie A Pasco
BONE | ELSEVIER SCIENCE INC | Published : 2015
PURPOSE: The WHO fracture risk prediction tool (FRAX®) utilises clinical risk factors to estimate the probability of fracture over a 10-year period. Although falls increase fracture risk, they have not been incorporated into FRAX. It is currently unclear if FRAX captures falls risk and whether addition of falls would improve fracture prediction. We aimed to investigate the association of falls risk and Australian-specific FRAX. METHODS: Clinical risk factors were documented for 735 men and 602 women (age 40-90 yr) assessed at follow-up (2006-2010 and 2000-2003, respectively) of the Geelong Osteoporosis Study. FRAX scores with and without BMD were calculated. A falls risk score was determined..View full abstract
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Awarded by National Health and Medical Council
The study was funded by grants from the National Health and Medical Council (NHMRC 251638, 299831, 628582), The University of Melbourne Research Grant Scheme, American Society for Bone and Mineral Research (ASBMR), Perpetual Trustees, Amgen (Europe) GmBH and the Geelong Region Medical Research Foundation.