Journal article

A Proteomics and Transcriptomics Investigation of the Venom from the Barychelid Spider Trittame loki ( Brush- Foot Trapdoor)

Eivind AB Undheim, Kartik Sunagar, Volker Herzig, Laurence Kely, Dolyce HW Low, Timothy NW Jackson, Alun Jones, Nyoman Kurniawan, Glenn F King, Syed A Ali, Agostino Antunes, Tim Ruder, Bryan G Fry

TOXINS | MDPI | Published : 2013

Abstract

Although known for their potent venom and ability to prey upon both invertebrate and vertebrate species, the Barychelidae spider family has been entirely neglected by toxinologists. In striking contrast, the sister family Theraphosidae (commonly known as tarantulas), which last shared a most recent common ancestor with Barychelidae over 200 million years ago, has received much attention, accounting for 25% of all the described spider toxins while representing only 2% of all spider species. In this study, we evaluated for the first time the venom arsenal of a barychelid spider, Trittame loki, using transcriptomic, proteomic, and bioinformatic methods. The venom was revealed to be dominated by..

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Grants

Awarded by F.C.T (Fundacao Fundacao para a Ciencia Ciencia e a Tecnologia)


Awarded by F.C.T


Awarded by ARC


Funding Acknowledgements

BGF was funded by the Australian Research Council (ARC) and the University of Queensland. KS was funded by the PhD grant (SFRH/BD/61959/2009) from F.C.T (Fundacao Fundacao para a Ciencia Ciencia e a Tecnologia). AA was funded by the project PTDC/AAC-AMB/121301/2010 (FCOMP-01-0124-FEDER-019490) from F.C.T. EABU acknowledges funding from the University of Queensland (International Postgraduate Research Scholarship, UQ Centennial Scholarship, and UQ Advantage Top-Up Scholarship) and the Norwegian State Education Loans Fund. SAA was the recipient of postdoctoral fellowship (PDRF Phase II Batch-V) from Higher Education Commission (HEC Islamabad) Pakistan. TNJW was funded by the award of post-graduate scholarship by the University of Queensland. GFK acknowledges support from ARC Discovery Grant DP130103813. Robert Raven of the Queensland Museum provided positive identification of the spider species.