Journal article

Age-Related Macular Degeneration in Ethnically Diverse Australia: Melbourne Collaborative Cohort Study

Liubov D Robman, Fakir MA Islam, Elaine WT Chong, Madeleine KM Adams, Julie A Simpson, Khin Zaw Aung, Galina A Makeyeva, John L Hopper, Dallas R English, Graham G Giles, Paul N Baird, Robyn H Guymer



PURPOSE: To determine and compare the prevalence of age-related macular degeneration (AMD) in older Australians of Anglo-Celtic and Southern European origin. METHODS: A total of 21,132 participants of the Melbourne Collaborative Cohort Study, aged 47-86 years, were assessed for AMD in 2003-2007 with non-mydriatic fundus photography. Of these, 14% were born in Southern Europe (Greece, Italy or Malta), with the remaining 86% of Anglo-Celtic origin, born in Australia, the United Kingdom or New Zealand. RESULTS: Overall, 2694 participants (12.7%) had early stages of AMD, defined as either one or more drusen ≥ 125 μm (with or without pigmentary abnormalities) or one or more drusen 63-124 μm with ..

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Awarded by National Health & Medical Research Council of Australia (NHMRC)

Awarded by NHMRC

Awarded by NHMRC Centre for Clinical Research Excellence Grant

Funding Acknowledgements

Cohort recruitment was funded by VicHealth and The Cancer Council Victoria. Further MCCS funding: the National Health & Medical Research Council of Australia (NHMRC) Program Grant 209057, Capacity Building Grant 251533 and Enabling Grant 396414. The ophthalmic component was funded by the Ophthalmic Research Institute of Australia; American Health Assistance Foundation, Jack Brockhoff Foundation, John Reid Charitable Trust, Perpetual Trustees and Royal Victorian Eye and Ear Hospital. People support was provided through the NHMRC Career Development (300052) and Practitioner (529905) Fellowships to RHG, Wagstaff Fellowship to LR, NHMRC PhD scholarship (590226) and Hugh Noel Puckle Scholarship to MA, NHMRC Senior Research Fellowships to PNB (1028444) and JH (1023434), and Novartis Medical Retinal Fellowship to EC. Centre for Eye Research Australia is a recipient of the NHMRC Centre for Clinical Research Excellence Grant 529923 and Operational Infrastructure Support from the Victorian Government. The funding organizations did not have any involvement in study design and data collection, analysis or interpretation.