Journal article

EFFECT OF CHRONIC ELECTRICAL-STIMULATION ON COCHLEAR NUCLEUS NEURON SIZE IN NORMAL-HEARING KITTENS

DF NI, HL SELDON, RK SHEPHERD, GM CLARK

ACTA OTO-LARYNGOLOGICA | SCANDINAVIAN UNIVERSITY PRESS | Published : 1993

Abstract

Very young cochlear-implant candidates may have undetected islands of residual hearing. Would the maturation of these functioning auditory neurons be affected by chronic cochlear stimulation? This was tested by examining neuron sizes in the cochlear nuclei of young, normal hearing kittens with and without chronic cochlear stimulation. Six animals received bilateral intra- or extracochlear implants and were electrically stimulated unilaterally for periods of 1,000-1,500 hours. After sacrifice, cross-sectional areas of approximately 11,000 neurons somata in the cochlear nuclei were measured with an image-analysis system. There were statistically significant differences between stimulated and u..

View full abstract

University of Melbourne Researchers