Journal article

SURVEILLANCE AND EARLY DIAGNOSIS OF COLORECTAL-CANCER

SJ WINAWER, P PROROK, F MACRAE, SP BRALOW

CANCER DETECTION AND PREVENTION | BLACKWELL SCIENCE INC | Published : 1985

Abstract

Colorectal cancer is a major health problem in western countries such as the United States. The annual incidence of more than 130,000 new cases, and the annual mortality of more than 60,000 people justifies a consideration of efforts for its control. New concepts of risk, better understanding of the adenoma-adenocarcinoma natural history, and new screening and diagnostic technology have provided a basis for possible preventive approaches. Trials are in progress evaluating the fecal occult blood test and sigmoidoscopy screening tests, and colonoscopy as a diagnostic and surveillance test. Evaluation of data from the trials requires many considerations regarding bias and validity. Although the..

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