Correlation of chromatic, spatial, and temporal sensitivity in optic nerve disease

Abstract

Spearman rank-order correlations (R) were made between the color-mixture threshold, spatial contrast sensitivity, and flicker sensitivity measurements of 38 patients with a variety of optic nerve disorders. Patients had to satisfy the following criteria: >0.5 log unit loss of chromatic or achromatic sensitivity (compared to age-matched normals), central fixation, no congenital color defects, and no ocular media abnormalities. The results of the analysis show a significant correlation between selective losses of high spatial frequency sensitivity (relative to low) and selective losses of red/green and blue/yellow sensitivities [R = -0.680 (P < 0.001) and R = - 0.439 (P < 0.01), respectively]...