Journal article

A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors

Shane M Devine, San Sui Lim, Lndu R Chandrashekaran, Christopher A MacRaild, Damien R Drew, Cael O Debono, Raymond Lam, Robin F Anders, James G Beeson, Martin J Scanlon, Peter J Scammells, Raymond S Norton

RSC Medicinal Chemistry | ROYAL SOC CHEMISTRY | Published : 2014

Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)


Funding Acknowledgements

The authors would like to thank Brad Sleebs for fruitful discussions on this project, Samuel Hughes for preliminary work on the synthesis, and Jason Dang for obtaining HRMS data. This work was supported in part by an Australian National Health and Medical Research Council (NHMRC) project grant (1025150) and program grant (637406). R.S.N. and J.G.B acknowledge fellowship support from the NHMRC. The Burnet Institute is supported by the NHMRC Independent Research Institutes Infrastructure Support Scheme, and Operational Infrastructure Support from the State Government of Victoria, Australia.