Cognitive Outcomes Following Arterial Ischemic Stroke in Infants and Children
Christine A Hajek, Keith Owen Yeates, Vicki Anderson, Mark Mackay, Mardee Greenham, Alison Gomes, Warren Lo
JOURNAL OF CHILD NEUROLOGY | SAGE PUBLICATIONS INC | Published : 2014
This study sought to investigate cognitive outcomes following pediatric arterial ischemic stroke and explore predictors. Participants included 36 children with perinatal or childhood arterial ischemic stroke and a comparison group of 15 children with asthma. Outcomes included cognitive ability, executive functions, and neurological function (Pediatric Stroke Outcome Measure). Magnetic resonance imaging measured lesion location and volume. Mean cognitive scores were at the low end of the average range. Children with arterial ischemic stroke performed significantly below normative populations and significantly below the asthma group on inhibitory control (Cohen's d = .68). Both the Pediatric S..View full abstract
Awarded by Research Institute at Nationwide Children's Hospital
WL was supported by the Research Institute of the Nationwide Children's Hospital. KOY is supported by the NIH, although no NIH funds were expended in this study. VA is supported by the National Health and Medical Research Council of Australia. The remaining authors have no financial disclosures and declare no conflicts of interest. The larger study on which the research was based was supported by grant 231308 from the Research Institute at Nationwide Children's Hospital, the Murdoch Childrens Research Institute, and the Victorian Governmental Operational Infrastructure Scheme.