Journal article

Defence against the immune barrage: Helminth survival strategies

M Riffkin, HF Seow, D Jackson, L Brown, P Wood

IMMUNOLOGY AND CELL BIOLOGY | WILEY | Published : 1996

Abstract

Parasites have generated a range of countermeasures against the host immune system which allows their survival long enough for reproduction to occur. Parasite subsistence is enhanced by evasion of the immune response utilizing mechanisms such as antigenic variation of exposed immunogenic proteins, shedding of surface proteins which are the target of an immune response, and protease production to neutralise specific anti-parasite immune components. Recent advances in the fields of immunology and parasitology have highlighted a range of mechanisms by which the parasite actively modulates the immune response to allow survival. Parasite factors can directly suppress the function of certain subse..

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