Journal article

Adverse childhood experiences and gender influence treatment seeking behaviors in obsessive-compulsive disorder

Francesco Benedetti, Sara Poletti, Daniele Radaelli, Elena Pozzi, Chiara Giacosa, Enrico Smeraldi

COMPREHENSIVE PSYCHIATRY | W B SAUNDERS CO-ELSEVIER INC | Published : 2014

Abstract

BACKGROUND: Exposure to adverse childhood experiences (ACE) increases the risk of adult physical and mental health disorders, including obsessive-compulsive disorder (OCD), and influences adult brain structure and function. ACE could influence the use of psychotropic drugs in adulthood, and treatment seeking behaviors. METHODS: We assessed the severity of ACE in a sample of 31 healthy controls and 66 patients with OCD who were consecutively referred for hospitalization and were either drug-naïve or drug-treated. In addition, we explored the possible clinical relevance of ACE with two additional analyses: (a) a discriminant function analysis with sex and ACE as factors, and (b) a logistic reg..

View full abstract

University of Melbourne Researchers