Signalling through CSF receptors

Abstract

The finely regulated process o f blood cell formation is under the control of a family o f glycoprotein hormones, known as colony-stimulating factors (CSFs), and their receptors. The complexity o f the intracellular mechanisms involved in the action of such factors has been appreciated only recently. In this review, Gino Vairo and John Hamilton discuss the biochemistry o f CSF action and its relevance to growth control, and examine the possibility that different CSFs may use common control pathways within the one cell type. © 1991.