Journal article

Influence of light exposure during early life on the age of onset of bipolar disorder

Michael Bauer, Tasha Glenn, Martin Alda, Ole A Andreassen, Elias Angelopoulos, Raffaella Ardau, Christopher Baethge, Rita Bauer, Bernhard T Baune, Frank Bellivier, Robert H Belmaker, Michael Berk, Thomas D Bjella, Letizia Bossini, Yuly Bersudsky, Eric Yat Wo Cheung, Joern Conell, Maria Del Zompo, Seetal Dodd, Bruno Etain Show all

Journal of Psychiatric Research | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2015

Abstract

BACKGROUND: Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association. METHODS: Data collected previously at 36 collection sites from 23 countries were available for 3896 patients with bipolar I disorder, born between latitudes of 1.4 N and 70.7 N, and 1.2 S and 41.3 S. Hours of daylight variables for th..

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