Influence of light exposure during early life on the age of onset of bipolar disorder
Michael Bauer, Tasha Glenn, Martin Alda, Ole A Andreassen, Elias Angelopoulos, Raffaella Ardau, Christopher Baethge, Rita Bauer, Bernhard T Baune, Frank Bellivier, Robert H Belmaker, Michael Berk, Thomas D Bjella, Letizia Bossini, Yuly Bersudsky, Eric Yat Wo Cheung, Joern Conell, Maria Del Zompo, Seetal Dodd, Bruno Etain Show all
Journal of Psychiatric Research | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2015
BACKGROUND: Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association. METHODS: Data collected previously at 36 collection sites from 23 countries were available for 3896 patients with bipolar I disorder, born between latitudes of 1.4 N and 70.7 N, and 1.2 S and 41.3 S. Hours of daylight variables for th..View full abstract
We thank the European College of Neuropsychopharmacology (ECNP) Network Initiative for supporting the European Network of Bipolar Research Expert Centres (ENBREC) involved in this research.