Blastocyst culture and transfer increases the efficiency of oocyte donation

Abstract

OBJECTIVE: To determine the impact of blastocyst transfer on an oocyte donation program. DESIGN: Retrospective review of embryo transfer in an IVF clinic. SETTING: Private assisted reproductive technology unit. PATIENT(S): Two hundred and twenty nine patients undergoing oocyte donation. INTERVENTION(S): Culture of pronucleate embryos to either day 3 or day 5 followed by embryo transfer. MAIN OUTCOME MEASURE(S): Implantation rates, pregnancy rates, and multiple gestations were analyzed. RESULT(S): Implantation rates and pregnancy rates were significantly increased by moving to extended embryo culture and transfer on day 5. After day 3 transfers, implantation and pregnancy rates were 47.1% and..