Journal article

Choice of population database for forensic DNA profile analysis

Christopher D Steele, David J Balding

SCIENCE & JUSTICE | ELSEVIER SCI LTD | Published : 2014

Abstract

When evaluating the weight of evidence (WoE) for an individual to be a contributor to a DNA sample, an allele frequency database is required. The allele frequencies are needed to inform about genotype probabilities for unknown contributors of DNA to the sample. Typically databases are available from several populations, and a common practice is to evaluate the WoE using each available database for each unknown contributor. Often the most conservative WoE (most favourable to the defence) is the one reported to the court. However the number of human populations that could be considered is essentially unlimited and the number of contributors to a sample can be large, making it impractical to pe..

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University of Melbourne Researchers

Grants

Awarded by UK Biotechnology and Biological Sciences Research Council


Awarded by Cellmark Forensic Services


Awarded by Biotechnology and Biological Sciences Research Council


Funding Acknowledgements

CDS is funded by a PhD studentship from the UK Biotechnology and Biological Sciences Research Council (BB/J012963/1) and Cellmark Forensic Services (CMD-PHD1).