One-Dimensional Haemodynamic Modeling and Wave Dynamics in the Entire Adult Circulation
Jonathan P Mynard, Joseph J Smolich
ANNALS OF BIOMEDICAL ENGINEERING | SPRINGER | Published : 2015
One-dimensional (1D) modeling is a powerful tool for studying haemodynamics; however, a comprehensive 1D model representing the entire cardiovascular system is lacking. We present a model that accounts for wave propagation in anatomically realistic systemic (including coronary and cerebral) arterial/venous networks, pulmonary arterial/venous networks and portal veins. A lumped parameter (0D) heart model represents cardiac function via a time-varying elastance and source resistance, and accounts for mechanical interactions between heart chambers mediated via pericardial constraint, the atrioventricular septum and atrioventricular plane motion. A non-linear windkessel-like 0D model represents ..View full abstract
J. P. Mynard acknowledges the support of a CJ Martin Early Career Fellowship from the National Health and Medical Research Council of Australia. This work was supported in part by the Victorian Government's Operational Infrastructure Support Program.