Mitochondrial function provides instructive signals for activation-induced B-cell fates
Kyoung-Jin Jang, Hiroto Mano, Koji Aoki, Tatsunari Hayashi, Akihiko Muto, Yukiko Nambu, Katsu Takahashi, Katsuhiko Itoh, Shigeru Taketani, Stephen L Nutt, Kazuhiko Igarashi, Akira Shimizu, Manabu Sugai
Nature Communications | NATURE PUBLISHING GROUP | Published : 2015
Awarded by Grants-in-Aid for Scientific Research
We thank Drs F. Alt (Harvard University), U. Basu (Harvard University) and J. Chaudhuri (Memorial Sloan-Kettering Cancer Center) for providing AID antibody; Drs K. Iwai (Kyoto University), Y. Sasaki (Kyoto University), H. Arakawa (National Cancer Center) and Y. Yokota (Fukui University) for discussion of the findings; Drs K. Ochiai (Tohoku University) and Y. Yokota (Fukui University) for critical reading of the manuscript; Dr M. Minami (Kyoto University) for comments on mitochondrial assay; Ms K. Furuta and Mr H. Koda (Kyoto University) for technical assistance in electron microscopy; Drs Okuno (Kyoto University) and Fukuura (PRIMETECH Corp) for the XF96 assay; Dr Takatani (Kyoto University) for comments on this study; and Mr K. Yoshida (Kyoto University) for supporting experiments. We thank Enago (www.enago.jp) for English language review. This work was supported in part by grants-in-aid for Science Research on Priority Areas from the Ministry of Education, Culture, Sports, Science and Technology of Japan. S.L.N. was supported by an Australian Research Council Future Fellowship and Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIIS.