Maternal cannabis use and birth weight: a meta-analysis

Abstract

AIMS: To estimate the effect of maternal cannabis use on birth weight. DESIGN: Meta-analysis of published observational studies adjusted for cigarette smoking. Separate analyses were performed for studies of low birth weight and mean birth weight. We used fixed and random effects models, but in all cases the results were identical. SETTING: From the Medline database, we identified 10 studies in which the results were adjusted for cigarette smoking. In seven studies, information on cannabis use was collected prenatally. Five studies reported results for differences in mean birth weight associated with maternal cannabis use. PARTICIPANTS: 32,483 women giving birth to live-born infants. MEASURE..