Baseline characteristics of the transient pattern electroretinogram in non-human primates: Inter-ocular and inter-session variability

Abstract

This study assessed the inter-ocular and inter-session variability of the transient pattern electroretinogram (PERG) in a group of non-human primates. The transient PERG was measured both eyes of 29 non-human primates, and again after three months in 23 eyes of 23 of these animals. Signals were elicited using a contrast (90%, 75cdm-2) reversing (5reversalssec -1) checkerboard pattern (0.56cpd). PERGs were also measured for stimuli of varied spatial frequency (n=8, 0.07-2.22cpd), contrast (n=4, 20-100%), mean luminance (n=4, 4.7-75cdm-2) and defocus (n=5, +1, +2, +3 diopters). The inter-eye and inter-session limits-of-agreement (LOA; 95%) were determined for each PERG parameter. Variability w..