Journal article
Father's environment before conception and asthma risk in his children: A multi-generation analysis of the Respiratory Health In Northern Europe study
C Svanes, J Koplin, SM Skulstad, A Johannessen, RJ Bertelsen, B Benediktsdottir, L Bråbäck, AE Carsin, S Dharmage, J Dratva, B Forsberg, T Gislason, J Heinrich, M Holm, C Janson, D Jarvis, R Jögi, S Krauss-Etschmann, E Lindberg, F Macsali Show all
International Journal of Epidemiology | Published : 2017
DOI: 10.1093/ije/dyw151
Abstract
Background: Whereas it is generally accepted that maternal environment plays a key role in child health, emerging evidence suggests that paternal environment before conception also impacts child health. We aimed to investigate the association between children's asthma risk and parental smoking and welding exposures prior to conception. Methods: In a longitudinal, multi-country study, parents of 24 168 offspring aged 2-51 years provided information on their life-course smoking habits, occupational exposure to welding and metal fumes, and offspring's asthma before/after age 10 years and hay fever. Logistic regressions investigated the relevant associations controlled for age, study centre, par..
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Awarded by Odd Berg Medical Research Foundation
Funding Acknowledgements
The RHINE III study was supported financially by the Norwegian Research Council (Grant No. 214123); the Bergen Medical Research Foundation, the Western Norwegian Regional Health Authorities (Grant No. 911 892 and 911 631); the Norwegian Labour Inspection, the Norwegian Asthma and Allergy Association; The Faculty of Health of Aarhus University (Project No. 240008); The Wood Dust Foundation (Project No. 444508795); The Danish Lung Association; the Swedish Heart and Lung Foundation; the Vardal Foundation for Health Care Science and Allergy Research; the Swedish Council for Working Life and Social Research; the Bror Hjerpstedt Foundation, the Swedish Asthma and Allergy Association; the Icelandic Research Council and the Estonian Science Foundation (Grant No. 4350).