Dwelling quietly in the rich club: brain network determinants of slow cortical fluctuations
Leonardo L Gollo, Andrew Zalesky, R Matthew Hutchison, Martijn van den Heuvel, Michael Breakspear
Philosophical Transactions of the Royal Society B Biological Sciences | ROYAL SOC | Published : 2015
For more than a century, cerebral cartography has been driven by investigations of structural and morphological properties of the brain across spatial scales and the temporal/functional phenomena that emerge from these underlying features. The next era of brain mapping will be driven by studies that consider both of these components of brain organization simultaneously--elucidating their interactions and dependencies. Using this guiding principle, we explored the origin of slowly fluctuating patterns of synchronization within the topological core of brain regions known as the rich club, implicated in the regulation of mood and introspection. We find that a constellation of densely interconne..View full abstract
Awarded by NHMRC
L.L.G. and M.B. acknowledge Australian Research Council (Centre of Excellence in Integrative Brain Function, CIBF) and the NHMRC (programme grant no. APP 1037196). R.M.H. acknowledges the Canadian Institute of Health Research (CIHR) postdoctoral fellowship and Brain and Behaviour Research Foundation NARSAD Young Investigator Grant. A.Z. is supported by the NHMRC Career Development Fellowship (GNT1047648).