Journal article

Renal allograft re-use and herpetic re-infection

Stella Setyapranata, Stephen G Holt, Kate J Wiggins, William R Mulley, Peter G Kerr, Anthony J Landgren, Damon P Eisen, Andrew Young, Helen Opdam, Amanda Robertson, Khashayar Asadi, Peter D Hughes



A middle-aged man received a kidney transplant from a deceased multi-organ donor. The recipient suffered cardiac arrest several days post-operatively and sustained hypoxic brain injury and was declared brain dead. Following the family's consent, the allograft kidney was retrieved and re-transplanted into a man with end-stage renal failure secondary to reflux nephropathy. The liver was not transplanted due to suspicion of fatty changes based on macroscopic appearance. After transplantation of other organs, liver histology revealed coagulative parenchymal necrosis with nuclear inclusions and moderate parenchymal cholestasis, suggestive of herpes viral hepatitis. Renal implantation biopsy showe..

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Funding Acknowledgements

SS, KJW, WRM, DE, AR, KA have no conflict of interest. SGH has received research funding and or honoraria from Amgen, Baxter, Gilead and Sanofi. PGK received speaker fees from Amgen and PDH have received support for travel expenses and conference attendance from Novartis, advisory board fees from Novartis and Alexion and speakers fees from Alexion.