Common germline polymorphisms associated with breast cancer-specific survival

A Pirie; Q Guo; P Kraft; S Canisius; DM Eccles; N Rahman; H Nevanlinna; C Chen; S Khan; J Tyrer; MK Bolla; Q Wang; J Dennis; K Michailidou; M Lush; AM Dunning; M Shah; K Czene; H Darabi; M Eriksson; D Lambrechts; C Weltens; K Leunen; C van Ongeval; BG Nordestgaard; SF Nielsen; H Flyger; A Rudolph; P Seibold; D Flesch-Janys; C Blomqvist; K Aittomäki; R Fagerholm; TA Muranen; JE Olsen; E Hallberg; C Vachon; JA Knight; G Glendon; AM Mulligan; A Broeks; S Cornelissen; CA Haiman; BE Henderson; F Schumacher; L Le Marchand; JL Hopper; H Tsimiklis; C Apicella; MC Southey; SS Cross; MWR Reed; GG Giles; RL Milne; C McLean; R Winqvist; K Pylkäs; A Jukkola-Vuorinen; M Grip; MJ Hooning; A Hollestelle; JWM Martens; AMW van den Ouweland; F Marme; A Schneeweiss; R Yang; B Burwinkel; J Figueroa; SJ Chanock; J Lissowska; EJ Sawyer; I Tomlinson; MJ Kerin; N Miller; H Brenner; K Butterbach; B Holleczek; V Kataja; VM Kosma; JM Hartikainen; J Li; JS Brand

Journal article

Common germline polymorphisms associated with breast cancer-specific survival

A Pirie, Q Guo, P Kraft, S Canisius, DM Eccles, N Rahman, H Nevanlinna, C Chen, S Khan, J Tyrer, MK Bolla, Q Wang, J Dennis, K Michailidou, M Lush, AM Dunning, M Shah, K Czene, H Darabi, M Eriksson Show all

Breast Cancer Research | Published : 2015

DOI: 10.1186/s13058-015-0570-7

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Abstract

© 2015 Pirie et al. Introduction: Previous studies have identified common germline variants nominally associated with breast cancer survival. These associations have not been widely replicated in further studies. The purpose of this study was to evaluate the association of previously reported SNPs with breast cancer-specific survival using data from a pooled analysis of eight breast cancer survival genome-wide association studies (GWAS) from the Breast Cancer Association Consortium. Methods: A literature review was conducted of all previously published associations between common germline variants and three survival outcomes: breast cancer-specific survival, overall survival and disease-free..

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University of Melbourne Researchers

Melissa Southey Author

Graham Giles Author

Roger Milne Author

Catriona McLean Author

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DESCRIPTION (provided by applicant): The broad objective of the Breast Cancer Family Registry (Breast CFR) is to establish and maintain a hy..

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Grants

Awarded by Sundhed og Sygdom, Det Frie Forskningsråd

Funding Acknowledgements

The COGS project was funded through a European Commission's Seventh Framework Programme grant (agreement number 223175 - HEALTH-F2-2009-223175). The Breast Cancer Association Consortium (BCAC) is funded by Cancer Research-UK (C1287/A10118 and C1287/A12014). Meetings of the BCAC have been funded by the European Union COST programme (BM0606). ELAN Program of the University Hospital Erlangen (BBCC).