Journal article

Corticospinal projection patterns following unilateral section of the cervical spinal cord in the newborn and juvenile macaque monkey

MP Galea, I DarianSmith

JOURNAL OF COMPARATIVE NEUROLOGY | WILEY | Published : 1997

Abstract

Immediately following a unilateral section of the midcervical spinal cord that interrupts the dorsolateral, lateral, and ventral columns, the macaque monkey has a severe flaccid paralysis on the side of the lesion. Recovery of hand function is rapid, and, although it is incomplete, within a few months, the monkey uses the initially disabled hand and fingers with considerable skill. We examined the accompanying changes in the pattern of projection of corticospinal neurons to the cervical spinal cord that occurred following such a lesion. Spinal section was done both in newborn and juvenile macaques, and the postlesion period was followed for up to 150 weeks. Corticospinal neuron populations w..

View full abstract