Journal article

Impact on Decisions to Start or Continue Medicines of Providing Information to Patients about Possible Benefits and/or Harms: A Systematic Review and Meta-Analysis

Rachel A Crockett, Stephen Sutton, Fiona M Walter, Megan Clinch, Theresa M Marteau, John Benson



BACKGROUND: The impact of providing information about medicines to patients on decisions about starting or continuing them is unknown. PURPOSE: To estimate the impact on decisions to start or continue medicines, of providing information to patients about possible benefits and/or harms. DATA SOURCES: Electronic searches from 1980 to October 2010; reference and citation searches of included studies. STUDY SELECTION: Two investigators assessed studies' eligibility against inclusion criteria: randomized or pseudorandomized trials; participants older than 16 years and deciding for themselves; one group received information about possible benefits and/or harms of a potentially beneficial medicine,..

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University of Melbourne Researchers


Funding Acknowledgements

Received 7 September 2010 from Psychology Department (at Guy's), Health Psychology Section, King's College London, London, UK (RAC, TMM) and General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (SS, FMW, MC, JB). The work reported in this article was supported by a grant from the National Institute for Health Research School for Primary Care Research. The authors thank Dr Julian Higgins, MRC Biostatistics Unit, Cambridge, for helpful advice on the meta-analysis. Revision accepted for publication 26 December 2010.