Journal article

Biomarkers for Psychiatry: The Journey from Fantasy to Fact, a Report of the 2013 CINP Think Tank

Elizabeth Scarr, Mark J Millan, Sabine Bahn, Alessandro Bertolino, Christoph W Turck, Shitij Kapur, Hans-Juergen Moeller, Brian Dean



BACKGROUND: A think tank sponsored by the Collegium Internationale Neuropsychopharmacologium (CINP) debated the status and prospects of biological markers for psychiatric disorders, focusing on schizophrenia and major depressive disorder. METHODS: Discussions covered markers defining and predicting specific disorders or domains of dysfunction, as well as predicting and monitoring medication efficacy. Deliberations included clinically useful and viable biomarkers, why suitable markers are not available, and the need for tightly-controlled sample collection. RESULTS: Different types of biomarkers, appropriate sensitivity, specificity, and broad-based exploitability were discussed. Whilst a num..

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Awarded by Australian Research Council

Awarded by National Health and Medical Research Council

Awarded by Medical Research Council

Funding Acknowledgements

This work was supported by the Australian Research Council (FT100100689 to Dr Scarr), BMBF QuantPro grant and the Max Planck Society (Dr Turck), and the National Health and Medical Research Council (#APP1002240 to Dr Dean). The authors would like to thank all participants of the Think Tank 2013 for their stimulating discussions and insightful questions, particularly Professor Angelos Halaris for his cogent summation. The 2013 Think Tank was sponsored by the International College of Neuropsychopharmacology (CINP).