Journal article

Tone Entropy Analysis of Foetal Heart Rate Variability

Ahsan Khandoker, Chandan Karmakar, Yoshitaka Kimura, Miyuki Endo, Sayaka Oshio, Marimuthu Palaniswami

ENTROPY | MDPI | Published : 2015


Development of the foetal autonomic nervous system can be indirectly understood by looking at the changes in beat to beat variability in foetal heart rates. This study presents Tone-Entropy (T-E) analysis of foetal heart rate variability (HRV) at multiple lags (1-8) to understand the influence of gestational ages (early and late) on the development of the foetal autonomic nervous system (ANS). The analysis was based on foetal electrocardiograms (FECGs) of 46 healthy foetuses of 20-32 weeks (early group) and 22 foetuses of 35-41 weeks (late group). Tone represents sympatho-vagal balance and entropy the total autonomic activities. Results show that tone increases and entropy decreases at all l..

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Awarded by Australian Research Council

Funding Acknowledgements

This work was supported by an Australian Research Council Linkage under Grant LP100200184 between the University of Melbourne, Tohoku University and Atom Medical Corporation in Japan. A part of the work was carried out under the Coordination, Support and Training Program for Translational Research, Ministry of Education, Culture, Sports, Science and Technology in Japan.