Journal article

Bone geometry of the hip is associated with obesity and early structural damage - a 3.0 T magnetic resonance imaging study of community-based adults

Andrew J Teichtahl, Yuanyuan Wang, Sam Smith, Anita Wluka, Michael Zhu, Donna Urquhart, Graham G Giles, Richard O'Sullivan, Flavia M Cicuttini

ARTHRITIS RESEARCH & THERAPY | BMC | Published : 2015

Abstract

INTRODUCTION: The mechanism by which obesity increases the risk of hip osteoarthritis is unclear. One possibility may be by mediating abnormalities in bony geometry, which may in turn be associated with early structural abnormalities, such as cartilage defects and bone marrow lesions. METHODS: One hundred and forty one older adults with no diagnosed hip osteoarthritis had weight and body mass index measured between 1990 and 1994 and again in 2009 to 2010. Acetabular depth and lateral centre edge angle, both measures of acetabular over-coverage, as well as femoral head cartilage volume, cartilage defects and bone marrow lesions were assessed with 3.0 T magnetic resonance imaging performed in ..

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Grants

Awarded by NHMRC Early Career Fellowship


Awarded by NHMRC Career Development Fellowships


Funding Acknowledgements

AJT is the recipient of the NHMRC Early Career Fellowship (#1073284). WY, AEW and DU are the recipients of NHMRC Career Development Fellowships (Clinical Level 1 #1065464, Clinical Level 2 #1063574 and Clinical Level 1 #1011975, respectively).