Serum β-hCG levels post-treatment of ectopic pregnancy with a single dose of intramuscular methotrexate

Abstract

Background The cytotoxic management of ectopic pregnancy using a single dose of intramuscular methotrexate injection has been well established as effective for a select number of women with unruptured tubal ectopic pregnancy where there are minimal symptoms. Aim The purpose of this study was to create centile curves of serum β-hCG levels following successful treatment with a single dose of 50 mg/m2 of intramuscular methotrexate to treat ectopic pregnancy. Material and Methods Data were retrieved from women treated at the Royal Women's Hospital for ectopic pregnancy between 2006 and 2012. Only women with minimal symptoms, initial serum β-hCG ≤5000 IU/L and ectopic mass size of ≤35 mm on ultra..