Journal article

Comparison of Single-fraction and Multi-fraction Stereotactic Radiotherapy for Patients with 18F-fluorodeoxyglucose Positron Emission Tomography-staged Pulmonary Oligometastases

S Siva, K Kirby, H Caine, D Pham, T Kron, L Te Marvelde, D Whalley, MJ Stevens, F Foroudi, M MacManus, D Ball, T Eade

Clinical Oncology | Published : 2015

Abstract

Aim: To compare outcomes of single-fraction and multi-fraction stereotactic ablative body radiotherapy (SABR) for pulmonary metastases. Materials and methods: A retrospective review from two academic institutions of patients with one to three pulmonary metastases staged with 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans. For single-fraction SABR, 26Gy was prescribed for peripheral targets and 18Gy for central targets. In the multi-fraction cohort, 48Gy/4 or 50Gy/5 was prescribed for peripheral targets and 50Gy/5 was prescribed for central targets. Three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT) and volume..

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