Journal article

Comparison of Single-fraction and Multi-fraction Stereotactic Radiotherapy for Patients with F-18-fluorodeoxyglucose Positron Emission Tomography-staged Pulmonary Oligometastases

S Siva, K Kirby, H Caine, D Pham, T Kron, L Te Marvelde, D Whalley, MJ Stevens, F Foroudi, M MacManus, D Ball, T Eade

CLINICAL ONCOLOGY | ELSEVIER SCIENCE LONDON | Published : 2015

Abstract

AIM: To compare outcomes of single-fraction and multi-fraction stereotactic ablative body radiotherapy (SABR) for pulmonary metastases. MATERIALS AND METHODS: A retrospective review from two academic institutions of patients with one to three pulmonary metastases staged with (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans. For single-fraction SABR, 26 Gy was prescribed for peripheral targets and 18 Gy for central targets. In the multi-fraction cohort, 48 Gy/4 or 50 Gy/5 was prescribed for peripheral targets and 50 Gy/5 was prescribed for central targets. Three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT) and..

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