Comparison of Single-fraction and Multi-fraction Stereotactic Radiotherapy for Patients with F-18-fluorodeoxyglucose Positron Emission Tomography-staged Pulmonary Oligometastases
S Siva, K Kirby, H Caine, D Pham, T Kron, L Te Marvelde, D Whalley, MJ Stevens, F Foroudi, M MacManus, D Ball, T Eade
CLINICAL ONCOLOGY | ELSEVIER SCIENCE LONDON | Published : 2015
AIM: To compare outcomes of single-fraction and multi-fraction stereotactic ablative body radiotherapy (SABR) for pulmonary metastases. MATERIALS AND METHODS: A retrospective review from two academic institutions of patients with one to three pulmonary metastases staged with (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans. For single-fraction SABR, 26 Gy was prescribed for peripheral targets and 18 Gy for central targets. In the multi-fraction cohort, 48 Gy/4 or 50 Gy/5 was prescribed for peripheral targets and 50 Gy/5 was prescribed for central targets. Three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT) and..View full abstract
Related Projects (1)
Awarded by National Health and Medical Research Council
Shankar Siva received National Health and Medical Research Council scholarship funding for this research, APP1038399.