Journal article

Retinal Vessels Change in Primary Angle-Closure Glaucoma: The Handan Eye Study

Jianlu Gao, Yuanbo Liang, Fenghua Wang, Ran Shen, Tienyin Wong, Yi Peng, David S Friedman, Ningli Wang

SCIENTIFIC REPORTS | NATURE PUBLISHING GROUP | Published : 2015

Abstract

Glaucoma is the second leading cause of blindness worldwide. To examine the relationship between angle closure and the retinal vessel diameter in Chinese adults, we conducted Handan Eye Study (HES), a large population-based cross-sectional study, which enrolled 6830 participants >30 year-old living in 13 randomly selected villages of Yongnian County. After adjusting for age, gender, spherical equivalent (SE), diabetes, and hypertension, the mean central retinal artery equivalent (CRAE, μm) was 127.1 ± 7.0 and 145.6 ± 4.4 in primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG), respectively; narrower than that in normal control (156.1 ± 0.4), primary angle-closure susp..

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Grants

Awarded by National Basic Research Program of China from the Ministry of Science & Technology of the People's Republic of China


Awarded by Key Technologies R&D Program from Bureau of Science and Technology of Handan city, Hebei Province, China


Funding Acknowledgements

This study was supported by National Basic Research Program of China (973 Program) Grant 2007CB512201 from the Ministry of Science & Technology of the People's Republic of China; program of Health Policy for Blindness Prevention from Ministry of Health the People's Republic of China; Key Technologies R&D Program (No. 2006-10903) from Bureau of Science and Technology of Handan city, Hebei Province, China; Beijing Tongren Hospital and the Key discipline fund of Bureau of Health, Handan city, Hebei Province, China.