Chronic recurrent multifocal osteomyelitis in children: Nine years' experience at a statewide tertiary paediatric rheumatology referral centre

Abstract

Objective. To describe the clinical features, management and outcome of 34 children with chronic recurrent multifocal osteomyelitis (CRMO) diagnosed at a single centre over 9 years. Methods. All children identified with CRMO for the period 2005-13 were identified from a prospectively collected database, with additional data from hospital records. Results. Thirty-four patients, 21 female and 13 male, were identified. The average age at symptom onset was 9.8 years (range 3.8-17.9) and at diagnosis was 10.9 years (range 5.2-18.2), with an average delay in diagnosis of 12 months. Follow-up was 0.3-7.9 years (average 2.1), with 104 individual bony lesions identified, with a median of 3 (range 1-9..