Journal article

Mitotic Spindle Orientation: Semaphorin-Plexin Signaling Flags the Way

Patrick O Humbert, Nathan J Goedde

DEVELOPMENTAL CELL | CELL PRESS | Published : 2015

Abstract

The extracellular signals and corresponding receptors that align the mitotic spindle of symmetrically dividing cells within an epithelial sheet are largely unknown. In this issue of Developmental Cell, Xia et al. (2015) identify semaphorin-plexin signaling as a regulator of spindle orientation critical for kidney development and repair.